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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEK1
All Species:
5.45
Human Site:
T967
Identified Species:
10
UniProt:
Q96PY6
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96PY6
NP_036356.1
1258
142828
T967
D
I
H
I
E
P
G
T
N
D
S
Q
H
S
K
Chimpanzee
Pan troglodytes
XP_001153129
1258
142786
T967
D
I
H
I
E
P
G
T
N
D
S
Q
H
S
K
Rhesus Macaque
Macaca mulatta
XP_001082793
1258
142958
A967
D
I
H
I
E
T
G
A
N
D
S
Q
H
S
K
Dog
Lupus familis
XP_543184
1286
146207
I995
E
V
D
K
R
P
E
I
D
D
S
Q
H
S
K
Cat
Felis silvestris
Mouse
Mus musculus
P51954
1203
136672
P919
D
P
A
V
D
D
S
P
Q
S
G
C
D
V
E
Rat
Rattus norvegicus
NP_001099552
648
74414
Q380
K
E
K
K
Q
K
D
Q
I
R
F
L
K
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513277
864
98961
E596
V
S
G
K
K
L
K
E
E
L
R
K
M
Q
V
Chicken
Gallus gallus
XP_420401
1281
145243
G987
Y
V
I
S
I
C
N
G
L
S
Y
T
A
S
E
Frog
Xenopus laevis
Q7ZZC8
944
104521
D676
N
E
R
P
Q
G
S
D
I
C
T
S
W
P
R
Zebra Danio
Brachydanio rerio
Q90XC2
697
76523
C429
F
G
S
G
S
N
G
C
L
G
H
G
N
F
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782796
1091
120115
K823
T
Q
I
D
S
A
P
K
T
Q
G
S
P
N
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9CAU7
606
68016
L338
N
R
E
R
Q
V
D
L
S
T
D
A
S
G
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48479
858
94329
T590
T
L
A
T
R
S
K
T
V
S
G
V
S
S
I
Conservation
Percent
Protein Identity:
100
99.6
97.5
85
N.A.
79.2
45.9
N.A.
30.2
66.2
22.4
22.7
N.A.
N.A.
N.A.
N.A.
32.9
Protein Similarity:
100
99.7
98.4
90.8
N.A.
85.6
48.5
N.A.
44.3
78
39.2
34.4
N.A.
N.A.
N.A.
N.A.
48.5
P-Site Identity:
100
100
86.6
46.6
N.A.
6.6
0
N.A.
0
6.6
0
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
86.6
66.6
N.A.
26.6
20
N.A.
13.3
20
26.6
13.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
N.A.
20.1
Protein Similarity:
N.A.
N.A.
N.A.
33.7
N.A.
35.1
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
0
0
8
0
8
0
0
0
8
8
8
0
% A
% Cys:
0
0
0
0
0
8
0
8
0
8
0
8
0
0
0
% C
% Asp:
31
0
8
8
8
8
16
8
8
31
8
0
8
0
8
% D
% Glu:
8
16
8
0
24
0
8
8
8
0
0
0
0
0
24
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% F
% Gly:
0
8
8
8
0
8
31
8
0
8
24
8
0
8
0
% G
% His:
0
0
24
0
0
0
0
0
0
0
8
0
31
0
0
% H
% Ile:
0
24
16
24
8
0
0
8
16
0
0
0
0
0
8
% I
% Lys:
8
0
8
24
8
8
16
8
0
0
0
8
8
0
31
% K
% Leu:
0
8
0
0
0
8
0
8
16
8
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
16
0
0
0
0
8
8
0
24
0
0
0
8
8
8
% N
% Pro:
0
8
0
8
0
24
8
8
0
0
0
0
8
8
0
% P
% Gln:
0
8
0
0
24
0
0
8
8
8
0
31
0
8
8
% Q
% Arg:
0
8
8
8
16
0
0
0
0
8
8
0
0
0
8
% R
% Ser:
0
8
8
8
16
8
16
0
8
24
31
16
16
47
0
% S
% Thr:
16
0
0
8
0
8
0
24
8
8
8
8
0
0
0
% T
% Val:
8
16
0
8
0
8
0
0
8
0
0
8
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _